Alpha Lipoic Acid- In first clinical trials, alpha-lipoic acid (ALA), managed to restore full liver function to 95% of the acute and severe liver damaged patients, when administered intravenously. Curative effects of ALA have been defined by the modulative regulation in eukaryotes. Lipoic acid has shown the ability to promote and boost the absorption of glucose to cell membranes; furthermore laboratory studies have shown that it can reduce triglycerides in blood. Besides the obviously high efficacy as an antioxidant, ALA has shown to be able to prevent vitamin C and vitamin E deficiency, the use as a chelator is still in the test phase; ALA in combination with L-carnitine shows improved mental performances in tests, paired with a postponed structural mitochondrial decay, making it a candidate in combating Alzheimer’s and Parkinson’s diseases.

Bioperine is derived from the extract of Piper nigrum L (black pepper) or Piper longum L (long pepper). Bioperine activates the thermogenesis process that generates energy at the cellular level. This process also helps in burning of fats. It also increases the absorption of nutrients and vitamins. It ensures that the body benefits and is able to efficiently use the nutrients from the food. It also boosts the metabolism that makes it effective in weight loss and maintenance. Because of the boost in metabolism, it also provides the body an increased supply of energy. It also aids in the proper digestion.

Caffeine, a central nervous system stimulant used in Goliath Labs Thermoloid as an aid to stay awake, for mental alertness due to fatigue or, in combination with other ingredients for pain relief, and as a power and energy accelerate. Caffeine is available alone as a non-prescription drug over the counter medication, in combination with other non-prescription drugs, and in prescription drug combinations for relief of pain and headache. Like Ephedra, caffeine acts to increase mental alertness while providing additional energy for weight loss and exercise training. Caffeine is more than a stimulant as it goes deep into muscles to provide long lasting power while delaying the onset of muscle fatigue. Also great before working out, caffeine fights fatigue and helps you get ready for your workout. For dieters feeling sluggish that need just a little something extra to get them through the day, caffeine is the obvious no-calorie stimulant solution. Many products containing caffeine anhydrous contain as much caffeine as one or two cups of coffee. It is recommended to limit the use of caffeine containing medications, foods, or beverages while taking caffeine supplements as excess caffeine intake may cause nervousness, irritability, sleeplessness and occasional rapid heart beat.

Cha De Bugre Extract is derived from the plant that grows in Brazil. It has been used for a long time for weight loss and appetite suppression. It contains potassium, allantoin and allantoic acid that stimulates the metabolism. It helps by burning the stored fats and uses it as energy source. It gives as sense of fullness that allows an individual to eat less. It helps increase the blood circulation and boosts energy and alertness. It helps control blood sugar and blood cholesterol level which reduces the risks of cardiovascular problem. It is a mild diuretic that prevents water retention and bloating. Cha De Bugre Extract also improves the immune system that fights against infections.

Chitosan is a safe remedy when you want to lose excess fat. It is a natural agent made by powdering the shells of shellfish like crabs and lobsters. Chitosan acts as a super fibre and attracts the fats, not allowing them to be absorbed by the blood. These fats are directly eliminated from the body in the stools. With no additional fats, the stored fats are used to produce energy leading to further weight loss. Being a fibre, it is known to improve digestion and elimination of wastes. It is also believed to fight tumors, strengthen bones, control blood pressure and cholesterol. It prevents tooth decay, acidity and constipation. The benefits of chitosan have not been proven yet. People allergic to seafood and pregnant women should avoid it.

Chromium is a natural trace mineral in human nutrition and is needed for proper metabolism of sugar in humans. It is vital for metabolism of fats and carbohydrates. It helps move blood sugar from the bloodstream into cells to be utilized as energy and turn fats, carbohydrates, and proteins into energy. Chromium helps stimulate fatty acid and cholesterol synthesis, which are needed for brain function and other body processes. It activates numerous enzymes that are required to drive many chemical reactions essential to life. Chromium supplements also improve glucose tolerance in people with Turner's syndrome, a disease associated with glucose intolerance. It is also vital for insulin metabolism. It regulates hunger and decreases cravings.

Citrus Aurantium is a fruit from the citrus family. Although later replaced by the sweet orange in recognition, it has retained many practical uses both in home remedies and in food. Citrus Aurantium boosts up the metabolism, which converts fat deposits into energy. Extensive use may help to control weight and hold back the effects of obesity. It can work as an appetite suppressant to restrain overeating. Citrus Aurantium can help to reduce chest congestion and coughs. Citrus Aurantium is a potent energy booster.

Conjugated Linoleic Acid or CLA is a non-essential fatty acid that may be found in cow and sheep meat, and dairy products. It is known to decrease body fat in obese and overweight people. It works by inhibiting the action of the lipoprotein lipase (LPL) enzyme that is responsible for the transfer of fat from the blood stream to the fats cells. It has powerful anti-carcinogenic properties that fight free radical cells from damaging the cells. It also helps control blood sugar levels. It encourages muscle growth and improves the metabolism which accelerates weight loss. It reduces the risk of heart diseases. It is also an antioxidant.

Evodia Rutaecarpa has been used in China by the native medicine and herbology practitioners for centuries as a weight loss agent. The Tetradium plant, as it is also known, as well as the bee bee tree, is native to Asia and the chemical associated with the weight loss effect has been isolated as evodiamine. In trials on mice it has been proven that the uptake of fat was significantly reduced by the specimen receiving the Evodia Rutaecarpa extract. While human testing was never truly conducted, the use of Evodia Rutaecarpa extracts in weight loss products seems to prove the interaction with the uncoupling protein 1, or UCP1, also named thermogenin. The stimulation of thermogenin by Evodia Rutaecarpa extract leads to energy being burned as heat, burning excess calories and consequently stored fat.

Green Tea Extract is of immense use to treat body ache, headaches and poor digestion. The green tea extract contains polyphenols to high levels and is an opulent source of antioxidant. It has the power of fighting free radicals more than vitamin E. the polyphenols present in green tea extract protect against respiratory and digestive infections. It blocks the carcinogens actions that promotes cancer and reduces the cholesterol levels. Green tea extract helps in metabolizing fat. The dieters can feel the weight loss without side effects and jitters. The green tea extract decreases the heart disease risk and also helps in preventing liver failure. The benefits of green tea extract are many, but as it contains caffeine, medical experts should be consulted prior to using it. Green tea extract also defends dental plaque. Green tea extracts prevents even liver transplant failure, but pregnant women should take green tea only after doctor consultation.

Guarana Extract is the extract of the guarana plant. It contains a significant amount of guaranine, a substance that is similar to caffeine found in coffee beans. It helps stimulate the adrenal glands and increase the production and release of hormones such as epinephrine, norepinephrine (adrenaline), and dopamine. This helps the metabolism of the body that enhances fat loss, and increases energy and endurance. It helps the body burn the fats to be used for energy. It aids in fighting stress, weakness and fatigue. As a stimulant, it also improves mental alertness, clarity, focus, concentration, and memory retention. Guarana also also improves the libido or sex drive in both men and women. Guarana also contains tannins that help prevent diarrhea and soothes the digestive system.

Guggulsterone is a plant sterol found in the resin of the guggul plant, Commiphora mukul. It acts as an antagonist of the farnesoid X receptor, which was earlier believed to result in decreased cholesterol synthesis in the liver.

Hoodia Gordonii is a succulent from the family Apocynaceae. It is a native plant of South Africa and Namibia. It is also commonly known as Bushman's Hat and Queen of the Namib. In appearance Hoodia gordonii is similar to cactus, but it has large tan colored flowers with strong smell. It has been used in traditional medicine for weight loss since a long time. It is increasingly being used in modern weight loss supplements because research has shown its appetite suppressant effects. Hoodia gordonii is not currently on the list of endangered species, but it is feared to become endangered if its excessive foraging and trade is not controlled.

L-Carnitine is chemically similar to an amino acid, L-Carnitine is responsible for the metabolism of fat in the body. It transports fatty acids into the cell’s metabolic furnace known as mitochondria. Synthesized in the liver and kidney, L-Carnitine helps the body use fat for energy. It acts as an aid in releasing tryglycerides and stored body fat into the bloodstream. With an adequate intake of L-Carnitine, you can improve the contraction of muscles, function of the heart and balance of protein in the body. As compared to the synthetic fat burning supplements that cause insomnia and addiction, L-Carnitine is a natural component which brings fat to metabolizing stations so that it can burn and produce energy. In case you have carnitine deficiency, you can have 1000mg of tartrate per day which is considered to be an effective form of carnitine.

Theobromine, which is a mild diuretic and mild stimulant. Theobromine can be found in cocoa and chocolate products. Theobromine is most commonly used for its diuretic effect.

White Kidney Bean Extract- Phaseolus vulgaris, or the common bean, exists in many varieties. One of such varieties is a popular Italian version, Cannellini beans, in the United States labeled often as white kidney beans. While several healthy ingredients warrant a healthy application of these beans, in particular the body building community is using a white kidney bean extract as a nutritional supplement for weight loss purposes. While there is no magic behind the formula, the idea behind the lipogenic effect of the white kidney bean extract seems sound. Although many people seem to dispute this particular aspect, other nutrients, like thiamine, Vitamin B6, folic acid, selenium, potassium, iron, molybdenum, as well as the high levels of protein, starch and dietary fiber, make this product a body building priority.

White Willow Extract is known to contain salicin. Salicin is converted by the body into salicylic acid which is the basis for aspirin. This natural extract is commonly used to treat pain, fever and inflammation especially low back pain, osteoarthritis, headache and fever. White willow extract has fewer side effects than aspirin but can cause minor stomachs upset and is not recommended for those allergic to aspirin, but can be a great supplement for those who find that aspirin makes them nauseous.

Yerba Matte- The plant of the yerba maté, as yerba matte is actually called, is a small tree or a shrub which can grow up to a size of fifteen meters. The leaves and twigs have traditionally been used to brew a tea like concoction, which is still a very popular social beverage in South America. Yerba maté contains alcaloids that are very similar to caffeine, commonly referred to as xanthines, but also elements like manganese, magnesium and potassium. The main difference between yerba maté and coffee, for instance, is the effect it has on muscle tissue, where it appears to relax smooth muscle tissue, but stimulate heart tissue and that is why it is used in Goliath Labs Thermoloid. In other studies, yerba maté was found to work as a monoamine oxidase inhibitor, thereby professing antidepressant qualities.