Caffeine- The bitter, white crystalline xanthine alkaloid caffeine is found in tea, coffee, soft drinks, chocolates, pain relievers, and a variety of over the counter medications. It is a psychoactive stimulant drug that causes increased alertness by stimulating the central nervous system. For the same reason, many people feel more energetic after consuming it. It even elevates the mood but these effects do not last for long. The effects of caffeine usually last for about five to six hours, though caffeine sensitivity varies from person to person. It has been found that people who consume lot of caffeine on a daily basis soon develop less sensitivity and may need to increase their intake to enjoy the same effect. Being a diuretic, a person consuming caffeine may have to urinate more often.

Chromium Polynicotinate is a more biologically active component than other forms of Chromium. CP helps to control blood sugar levels and can be dangerous to the blend of fats, cholesterol, and proteins. It is helpful in the metabolism of glucose and is important for getting energy. Chromium polynicotinate is a mineral that adds a hormone-like regulation to develop carbohydrate metabolism. As all carbohydrates finally are reduced to simple glucose in the body. Chromium polynicotinate provides the mediator action by plugging serum glucose through the bloodstream to the muscle cell directly. Chromium is essential for glucose regulation, carbohydrate metabolism, and energy production. It may also produce anabolic effects, but with no side effects.

Cocoa Seed Extract is the extract of the seeds of Theobroma cacao. It is cultivated for its seeds which are present in its pod shaped fruits. The extracts from its seeds have a number of health benefits. They are also used to make chocolate. Studies show that Cocoa extracts contain a high level of flavonoids, specifically epicatechin, which may have beneficial cardiovascular effects on health. The ingestion of flavonol-rich cocoa is associated with acute elevation of circulating nitric oxide, enhanced flow-mediated vasodilatation, and augmented microcirculation. Researchers also found that consumption of Cocoa can reduce risk of cancer and can reduce elevated blood pressure.

Evodiamine, an alkaloid extract from the Evodiae Fructus plant is known as Evodiamine. It has been referred to as a “hot nature” herb in Chinese literature and medicine. Based on animal studies, Evodiamine increases the natural fat burning rate and stimulates vanilloids for reduction of fat intake. It increases body temperature, influences the adrenal glands to secrete catecholamines and also affects the metabolism of certain drugs. Since it acts like a thermogenic and increases the overall temperature, more fat and calories are burnt due to its intake. This alkaloidal compound has anti obesity effects due to UCP1 (uncoupling protein 1) thermogenesis. In part, evodiamine can prevent diet induced obesity from developing further. It is available in the form of supplement or through Evodiae Fructus plant.

Garcinia Cambogia, native to Southeast Asia, is a tropical fruit which belongs to the citrus family. This Indian and African fruit is extremely popular for its extract hydroxycitric acid. Without suppressing your appetite or stimulating the brain, this acid acts as an effective weight loss supplement. It not only provides the required energy but also improves the signaling system of the body. When the signaling system gets better, the brain is informed by the body that it is full. This system is not very active in obese people, which is why they eat a lot. Garnicia Cambogia extract of hydroxycitric acid is more effectual when used with chromium. The intake of chromium in western countries is very low, due to which people become diabetic or obese.

Ginger Root- Zingiber officinale is the actual plant that grows an underground stem, commonly called ginger root and is a very popular spice, which also has medicinal properties. Main components of the ginger root are a mixture of volatile oils, zingerone, shogaols and gingerols, which have been found to display analgesic, antipyretic, antibacterial and sedative properties. Ginger also contains a fragrant essential oil, essentially consisting of sesquiterpenoids. As a spice, it is an important part of the Indian and Chinese cuisine, in the Western World it is known as the main ingredient in cookies, such as the gingerbread man, but also in the popular beverage ginger ale. Traditionally used as a treatment for nausea, diarrhea, motion sickness, general stomach settler, but also as a cold remedy, just recently properties for treatment of osteoarthritis and diabetes have been discovered.

Green Tea Extract- By increasing the body's metabolism, it is widely believed that green tea extract largely aids in weight loss.

Guarana is a climbing plant of the Sapindaceae family native to the Amazon basin. Guarana is best known for its fruit and seeds. Guarana extracts contain naturally high amounts of caffeine which the plant uses in defense against pathogens. Its extracts are a natural and abundant source of caffeine in most parts of the world. It is added to soft drinks, herbal tea, energy shots and used in capsules. The extracts have a positive effect on cognition and they also increase memory retention and physical endurance. A 2007 study on human pilots showed its positive effects on memory, alertness and mood. It is also reported to have antioxidant and antibacterial effects.

Hoodia Gordonii is a water retaining plant, also known as a succulent, which grows without leafs. Being native to the south of Africa, it has been in use for an indeterminable amount of time as an appetite suppressant. It is very easily identifiable, because the flowers of this plant have a rotten meat odor. The ingredient of the plant which is responsible for the appetite suppressing effects has been named P57. It is a steroidal glycoside which seems to act directly to the central nervous system’s mechanisms and supposedly raises the content of adenosine triphosphate in brain by at least a half. The effects of P57 in trials were registered as capable to reduce food intake by some fifty per cent on a daily basis.

Hordenine, which is also known as N-Dimethyl-hydroxyphenylethylamine, is a phenylethylamine alkaloid, which naturally occurs in barley seeds, but also in several cactus plants. The phenomenal antibiotic and antibacterial properties have long been recognized by the medical community, where in particular penicillin resistant Staphylococcus bacteria can be successfully restrained. Hordenine stimulates norepinephrine release and is therefore deemed a direct central nervous system stimulant. Norepinephrine, in turn, is a hormone that works as a lipolytic, aiding in liberating the stored fat from the cells and make it available for burning during the workout. The body building community commonly uses Hordenine as a weight loss agent. Furthermore, it seems that Hordenine is slowing down the digestive process, thereby slowing down the calorie transfer, allowing the excess fat to be burned, while retaining the feeling of satiation.

L-Tyrosine is an amino acid that may be found in foods such as meats, dairy products, wheat, fish, and oats. It plays an important role in the production of neurotransmitters such as L-dopa, dopamine, norepinephrine, and epinephrine that aids in the proper functioning of the brain. It prevents feelings of anxiety, irritability, frustration, sadness and depression. It also helps in losing weight because it aids in suppressing appetite and cravings. It also has the ability to enhance the libido. L-Tyrosine also protects the skin from UV light rays by being converted into melanin. It also benefits people with Alzheimer’s disease and dementia.

Octopamine, which is a trace amine, recently believed to be a lipotropic for fat loss. Octopamine has low oral bioavailability and is readily broken down by MAOI, as well as metabolized by the gut wall, which may mean it would not work well when taken orally, but more research is needed to prove its positive or negative effects.

Pantothenic Acid or vitamin B5 is a water soluble vitamin that may be found in various food sources such as fish, meat, broccoli, and egg yolk. It forms part of the coenzyme A (CoA) that is important in converting the food we ingest into energy. It stimulates the production and transportation of energy from fats. It also helps in maintaining a healthy digestive tract and prevents the liver from becoming fatty. Pantothenic acid is also known for preventing stress. It enhances the immune system and protects the body against various infections. Studies also showed that increases the level of zinc in the body that helps reduce acne and pimple breakouts.

Synephrine or oxedrine is a drug derived from bitter orange or Citrus aurantium. It is an aromatic compound with the systematic name 4-[1-hydroxy-2-(methylamino)ethyl]phenol which indicates that it has an attached hydroxyl group at para position and a methyl amino group at another position. It is not one of those compounds on which an extensive scientific study has been done. However, it has some positional isomers such as the neosynephrine as well as other compounds. Studies indicate that it could act as a Beta-3 adrenergic receptor which means that if taken as a supplement it enhances the breakdown of fat to release energy and also increases heat production in the muscles.

Vinpocetine is a derivitate of the periwinkle plant and was developed in the latter part of the 1960’s. It can be used as a dietary supplement, which can be found online.

White Willow Bark possesses salicin that offers identical effect as aspirin and exhibits no side effects. This is the basis for aspirin synthesis. Chinese healers used it to control pain and the Native Americans also understood the value of it to get relief from headaches as well rheumatism. This also reduces fevers. The advantage of white willow bark is that it also helps in reducing weight and aids the diet goals. It is an anti-inflammatory and is analgesic, anti-rheumatic, fever reducer and gives relief from inflammatory pains such as rheumatism, carpal tunnel syndrome and arthritis. White willow bark is found in Asia and Europe. Taking one or two capsules at mealtimes is recommended. However, this dosage should not be exceeded. This does not exhibit significant side effects, but the tannins present in the white willow extract may result in stomach upset and may trouble if a person is allergic to aspirin.

Yerba Matte Pronounced, YARE-ba MAH-tay, yerba mate is a shrub that belongs to the holly family. A Key Element in Thermo Hydroxadrine Yerba mate contains the following vitamins, minerals and additional compounds: Vitamin A to Vitamin C Vitamin E Vitamin B1 Vitamin B2 Vitamin Niacin Vitamin B5 Vitamin B complex Minerals: Calcium Iron Manganese Magnesium Potassium Phosphorus Selenium Additional Compunds: Flavonols Polyphenols Antioxidants Pantothenic Acid and more The leaves of yerba mate have been found to offer strength while the stems inspire energy.