Caffeine is a methylated xenthine discovered in 1819 by Friedrich Ferdinand Runge, a German chemist. Sources of Caffeine include beans, fruit and leaves of some plants. Caffeine available for human consumption is most commonly extracted from the coffee plant cherries and tea bush leaves, as well as foods and drinks that contain products derived from the kola nut. Caffeine can temporarily reduce the sensation of being tired; however, this does not mean that it eliminates the need for sleep. Generally, twenty five to fifty milligrams of caffeine is enough for most consumers to report an increase in alertness and arousal. Caffeine should be not be consumed by those with fecal incontinence as it relaxes the internal anal sphincter muscles.

Chromium Polynicotinate, which is a form of chromium, an essential trace mineral that is needed for the body's production of insulin. Insulin is a hormone that stabilizes the body's blood sugar level.

Cocoa Seed Extract, which is standardized for caffeine, tyramine, phenylethylamine and theobromine. Cocoa seed extract is thought to possibly help speed up the metabolism and provide feelings of fullness.

Evodiamine- Tetradii Fructus, the fruit of the evodia plant, also known as Tetradium rutaecarpa, contains an active element that has recently been identified as evodiamine. This chemical compound is believed to be somewhat similar to capsaicin, the active compound found in the chili peppers. Some studies suggested that this vanilloid receptor agonist may interact with thermogenin, otherwise known as the uncoupling protein 1, UCP1, which is able to generate heat by a mechanism called thermogenesis. Tetradium rutaecarpa has been traditionally used in Chinese medicine for weight loss purposes and current studies seem to verify this information. Evodiamine has been embraced as a dietary supplement directed at weight loss, predominantly by the body building circles. This supplement is deemed to have energy burning and fat reducing, as well as diuretic properties.

Garcinia Cambogia is helpful for weight loss as it suppresses accumulation of body fats. It promotes fat oxidation, increases serotonin release and its availability in brain, normalizes lipid profiles and reduces serum leptin levels in overweight people. Garcinia cambogia extract improves mucosal defensive mechanisms in the stomach and, so, is a good protective agent against gastric ulcers. It reduces both the volume and acidity of gastric juice. It acts as an appetite suppressant and also enhances metabolism. Garcinia cambogia can be helpful for people who attempt to have a low carb diet. It helps improve energy levels and strengthen the immune system. Garcinia cambogia extract can increase mucosal defense means in stomach, thus helping with gastric ulcers. It can decrease stomach acidity, and increase defensive properties on gastric juices.

Ginger Root- Ginger is a spice which originated in Asia, where it is grown primarily in India and the Southeast of Asia. Currently it is used all over the world for culinary purposes. Several other uses, besides that of a spice, have been encountered, like in Ginger Ale, ginger tea, but also ginger beer. Gingerbread is perhaps the most popular example of ginger use, but historically it has been labeled as a stimulant and a carminative. Indonesia traditionally uses herbal preparations with ginger, which is supposed to reduce fatigue and help control all kind of digestive problems. Ginger is also known to help with morning sickness and is an ingredient in motion sickness remedies. Nausea in many forms, including chemotherapy, is treated with ginger as well.

Green Tea Extract- Camellia sinensis, or more commonly the tea plant is a genus of flowering plants which is generally being used to produce tea, including green tea, oolong, black tea, white tea and pu-erh tea, also called Bolay tea. The different oxidation process makes the final difference. Tea plants can grow out into a tree, but are generally pruned to allow for easy hand picking. While camellia sinensis is being cultivated all around the globe in tropical and subtropical regions, this South and Southeast Asian native is most popular when imported from India and China. Medical uses of tea stem from the traditional Chinese medicine, where it was used as a bronchodilator and to treat angina pectoris, coronary artery disease and peripheral vascular diseases. Green tea extract is used as appetite suppressant and thermogenesis increasing agent.

Guarana is a South American climbing plant belonging to the genus of trees and shrubs called Maple. This plant is common around the Amazon and very present in Brazil. The fruit of the guarana plant is being used in that country to produce a diversity of soft drinks and beverages, having the double caffeine content of the coffee bean. Other nutrients that are contained in the seed besides caffeine are protein, fat and starch, but also adenine, choline, guanine, resin, tannin and xanthine, just to name a few. The cognitive effects of guarana are well documented, but the appetite suppressant qualities of guarana are relatively new. A study has proven that a combination of yerba mate, guarana and damiana leads to a tenfold weight loss quantity when compared with a placebo.

Hoodia Gordonii, which although popular, has no published randomized controlled trials in humans to show hoodia is safe or effective in pill form. One study published in the September 2004 issue of Brain Research found that injections of p57 (The Active ingredient in Raw, Fresh Cut Hoodia, not dried) into the appetite center of rat brains resulted in altered levels of ATP, an energy molecule that may affect hunger. The animals receiving the P57 injections also ate less than rats that received placebo injections. However, this was an animal study and INJECTIONS IN THE BRAIN are very different from oral consumption, so it cannot be used to show that oral hoodia can suppress appetite in humans. Hoodia Gordonii is a succulent (a cactus of the aloe family) found in the Kalahari desert of South Africa. Most Hoodia Gordonii products contain very little, if any of the active ingredient needed to suppress hunger. Real Hoodia is very rare and is even an endangered plant. Most importantly, Hoodia has only demonstrated any effect in fresh, raw pieces of the plant. The effectiveness of powdered Hoodia has yet to be shown and may actually increase hunger. It's main use is as a cheap alternative to the more expensive weight loss herbs, which are the only alternative left after the banning of ephedra. Most supplement manufacturers can not use the more expensive weight loss herbs because it will result in a product that would be too expensive to compete with other more popular inexpensive diet supplements.

Hordenine has antibacterial and antibiotic properties and is another weight loss agent that also stimulates the central nervous system.

L-Tyrosine, a non-essential amino acid that is used to build protein. It is a precursor dopamine, as well as a precursor to norepinephrine and epinephrine. The body makes L-Tyrosine from the amino acid phenylalanine. Since L-Tyrosine is a precursor of Dopamine, it may raise mental alertness, making it of great use in exercise programs.

Octopamine is a secretion initially discovered in the salivary glands of the Octopus and hence the derivation of the name. it tendso to act as a neurotransmitter, transmitting messages from the neurons to the brain and vice versa. Octopamine has been found to have a tendency to release fat deposits from cells, thus aiding in the loss of weight. It is therefore being used as a slimming agent by most people, even though there is no concrete evidence that it does assist in weight loss, for sure. Octopamine is also believed to increase blood pressure levels when it is in combination with other weight loss stimulating supplements. Although not much is known about Octopamine, a deeper study is being conducted into its uses and effects.

Pantothenic Acid also known as B5 is a natural, inexpensive and safe form of curing acne. It is free from all negative side effects. It is best suited for people with oily skin as it stops the overproduction of oil within our body. It converts the carbohydrates and fats into energy effectively when synthesized with other Vitamin B. Additionally it also helps your body produce red blood cells and metabolizes fats. It plays a significant role in reducing physical and mental stress because it works along with the stress hormone producing adrenal gland. Pantothenic acid is present in all kinds of food and therefore our body gets sufficient amount of it. As it is impossible for our body to become deficient in pantothenic acid, there is no recommended daily amount of it. Eggs, whole grains and milk contain panthothenic acid in large numbers.

Synephrine is used in some products. It is also called oxedrine, and is an aromatic compound with a hydroxyl group at the para position of its benzene ring. It is derived from the fruit of Citrus aurantium, and can be taken orally or by injection. Its pharmacology is not extensively studied, but some health benefits are associated to it. It is believed to burn fat and help in weight loss. It also increases the metabolic rate and energy level. Further research might indicate more benefits of the product.

Vinpocetine- The lesser periwinkle plant named Vinca Minore consists of Vincamine, which is found in its leaves and Vinpocetine is derived from this natural substance found in the plant. In countries such as Japan and Europe, Vinpocetine is a prescribed medicine. It is popularly available in the online stores and countries such as Canada and the US as an effective supplement for diet. Vinpocetine is a great medicine in order to protect oneself from brain dementia. It has also been found to help treat Alzheimer’s disease. However, there is no strong recent evidence to prove its effect on the treatment of Alzheimer’s disease. Overall, it’s great to boost the brain. However, it has certain side effects such as anxiety, insomnia, indigestion, dry mouth, headache and many more.

White Willow Bark is used as an anti-inflammatory and treats pains such as joint pain, flu, fever, back pain and osteoarthritis.

Yerba Matte is believed to possess cancer-fighting properties and has shown to have a relaxing effect on muscle tissues and a stimulating effect on heart tissues.