Caffeine is a methylated xenthine discovered in 1819 by Friedrich Ferdinand Runge, a German chemist. Sources of Caffeine include beans, fruit and leaves of some plants. Caffeine available for human consumption is most commonly extracted from the coffee plant cherries and tea bush leaves, as well as foods and drinks that contain products derived from the kola nut. Caffeine can temporarily reduce the sensation of being tired; however, this does not mean that it eliminates the need for sleep. Generally, twenty five to fifty milligrams of caffeine is enough for most consumers to report an increase in alertness and arousal. Caffeine should be not be consumed by those with fecal incontinence as it relaxes the internal anal sphincter muscles.

Chromium Polynicotinate, which is a form of chromium, an essential trace mineral that is needed for the body's production of insulin. Insulin is a hormone that stabilizes the body's blood sugar level.

Cocoa Seed Extract, which is standardized for caffeine, tyramine, phenylethylamine and theobromine. Cocoa seed extract is thought to possibly help speed up the metabolism and provide feelings of fullness.

Evodiamine- Tetradii Fructus, the fruit of the evodia plant, also known as Tetradium rutaecarpa, contains an active element that has recently been identified as evodiamine. This chemical compound is believed to be somewhat similar to capsaicin, the active compound found in the chili peppers. Some studies suggested that this vanilloid receptor agonist may interact with thermogenin, otherwise known as the uncoupling protein 1, UCP1, which is able to generate heat by a mechanism called thermogenesis. Tetradium rutaecarpa has been traditionally used in Chinese medicine for weight loss purposes and current studies seem to verify this information. Evodiamine has been embraced as a dietary supplement directed at weight loss, predominantly by the body building circles. This supplement is deemed to have energy burning and fat reducing, as well as diuretic properties.

Garcinia Cambogia is helpful for weight loss as it suppresses accumulation of body fats. It promotes fat oxidation, increases serotonin release and its availability in brain, normalizes lipid profiles and reduces serum leptin levels in overweight people. Garcinia cambogia extract improves mucosal defensive mechanisms in the stomach and, so, is a good protective agent against gastric ulcers. It reduces both the volume and acidity of gastric juice. It acts as an appetite suppressant and also enhances metabolism. Garcinia cambogia can be helpful for people who attempt to have a low carb diet. It helps improve energy levels and strengthen the immune system. Garcinia cambogia extract can increase mucosal defense means in stomach, thus helping with gastric ulcers. It can decrease stomach acidity, and increase defensive properties on gastric juices.

Ginger Root is a dietary supplement that is not only used as a spice but has had a positive effect on some types of arthritis and raynauds disease.

Green Tea Extract- Camellia sinensis, or more commonly the tea plant is a genus of flowering plants which is generally being used to produce tea, including green tea, oolong, black tea, white tea and pu-erh tea, also called Bolay tea. The different oxidation process makes the final difference. Tea plants can grow out into a tree, but are generally pruned to allow for easy hand picking. While camellia sinensis is being cultivated all around the globe in tropical and subtropical regions, this South and Southeast Asian native is most popular when imported from India and China. Medical uses of tea stem from the traditional Chinese medicine, where it was used as a bronchodilator and to treat angina pectoris, coronary artery disease and peripheral vascular diseases. Green tea extract is used as appetite suppressant and thermogenesis increasing agent.

Guarana is a South American climbing plant belonging to the genus of trees and shrubs called Maple. This plant is common around the Amazon and very present in Brazil. The fruit of the guarana plant is being used in that country to produce a diversity of soft drinks and beverages, having the double caffeine content of the coffee bean. Other nutrients that are contained in the seed besides caffeine are protein, fat and starch, but also adenine, choline, guanine, resin, tannin and xanthine, just to name a few. The cognitive effects of guarana are well documented, but the appetite suppressant qualities of guarana are relatively new. A study has proven that a combination of yerba mate, guarana and damiana leads to a tenfold weight loss quantity when compared with a placebo.

Hoodia Gordonii derives from a leafy plant and is utilized to suppress ones appetite.

Hordenine has antibacterial and antibiotic properties and is another weight loss agent that also stimulates the central nervous system.

L-Tyrosine is a protein non-essential building block Although non-essential it is important for the structure of body proteins. It has a direct effect on neurotransmitters.

Octopamine is a secretion initially discovered in the salivary glands of the Octopus and hence the derivation of the name. it tendso to act as a neurotransmitter, transmitting messages from the neurons to the brain and vice versa. Octopamine has been found to have a tendency to release fat deposits from cells, thus aiding in the loss of weight. It is therefore being used as a slimming agent by most people, even though there is no concrete evidence that it does assist in weight loss, for sure. Octopamine is also believed to increase blood pressure levels when it is in combination with other weight loss stimulating supplements. Although not much is known about Octopamine, a deeper study is being conducted into its uses and effects.

Pantothenic Acid is actually a part of the Vitamin B complex, namely Vitamin B5 and is deemed an essential nutrient. It has a critical function in the synthesis and metabolism of core nutrients, such as fats, proteins and carbohydrates, and it forms the coenzyme – A, also called CoA, most notable for the role in oxidation and synthesis of fatty acids and pyruvate. The Greek origin of the name Pantothenic Acid already states that this Vitamin is found nearly everywhere, with prominent amounts in eggs, meat, legumes and whole grain cereals. In health and fitness circles the dietary supplement is very popular for its energy producing role, but also for the ATP process and for the maintenance of cholesterol and triglycerides levels in the body.

Synephrine is used in some products. It is also called oxedrine, and is an aromatic compound with a hydroxyl group at the para position of its benzene ring. It is derived from the fruit of Citrus aurantium, and can be taken orally or by injection. Its pharmacology is not extensively studied, but some health benefits are associated to it. It is believed to burn fat and help in weight loss. It also increases the metabolic rate and energy level. Further research might indicate more benefits of the product.

Vinpocetine is available in capsule form. Vinpocetine has certain properties which helps move the right amount of blood to the brain from the body. It also enhances certain components of the body. The advantage of consuming this natural substance is it helps oxygen and blood flow to the brain, this helps overcome obstacles which form in the eyes. Many diagnosed with eye disorders that have an impact on the overall eyesight have successfully recovered after using this natural extract. It eliminates cognitive impairments which cause low metabolism, dangerous clots and memory loss. Ingestion of Vinpocetine seems to have a positive correlation with the healing of Tinnitus – the buzzing or ringing sensation in the ear, which is mainly caused due to the disruption of natural blood flow through the entire body. It greatly helps optimize your overall health conditions. Vinpocetine mainly contains the extract from the popular periwinkle plant.

White Willow Bark, which is often used as a natural alternative to aspirin, and is best not to be used by individuals allergic to aspirin. White willow bark extract offers little benefit to weight loss by itself but when used with other dietary supplements, it is thought to work as a thermogenic and help to elevate energy expenditure and promote the metabolsim of fat.

Yerba Matte, actually yerba maté, as it is called in Brazil, or Ilex paraguariensis in Latin, is a small tree or a shrub which can grow to fifteen meters. It is found naturally in South America, mainly in south of Brazil, Argentina, Paraguay, Uruguay and Chile. Foliage is evergreen, and the flowers are rather small, additionally there is a smallish fruit of red color. A tea like brewing in warm water, not boiling, is a popular drink in the native area, similar social gathering is common, akin to tea time practice in the United Kingdom. Yerba matte has several xanthines alkaloids which are related to caffeine, but although chemically identical to caffeine the mate xanthine cocktail provides different results, for instance it relaxes smooth muscle tissue and stimulates heart tissue. Yerba Matte is a potent ingredient in Thermo Hydroxadrine.